Mesodermale tumor

Malignant mixed mesodermal tumors (MMMTs) of the ovary are rare, highly aggressive neoplasms that arise most commonly in postmenopausal women. Histologically, they consist of a mixed population of malignant epithelial and mesenchymal elements SYMMONDS RE, DOCKERTY MB. Sarcoma and sarcoma-like proliferations of the endometrial stroma. I. A clinicopathologic study of 19 mesodermal mixed tumors. Surg Gynecol Obstet. 1955 Feb; 100 (2):232-240. HILL RP, MILLER FN., Jr Combined mesenchymal sarcoma and carcinoma (carcinosarcoma) of the uterus. Cancer. 1951 Jul; 4 (4):803-816 Kubosawa H, Nagao K, Kondo Y. A 68-year-old woman with a malignant mixed mesodermal tumor of the ovary is reported. Her clinical course worsened rapidly and she died 3 months after admission. At autopsy, the pelvic cavity was seen to be filled with a huge tumor mass. Histologically, the tumor contained malignant epithelial and mesenchymal elements Malignant mixed mesodermal tumor of ovary. Grover V, Dhall K, Grover RK, Choudhry T. A case of primary malignant mixed mesodermal tumor (MMMT) of the ovary arising de novo in a post-menopausal multiparous female is reported. The tumor contained heterologous elements in the form of cartilage and fat in addition to carcinosarcomatous areas Mixed mesodermal tumors of the uterus. Afonso JF. Two of five women with mixed mesodermal tumor of the uterus are well more than ten years after therapy. A third was well when last seen two years after therapy and died at age 84 but autopsy was not done

Maligne mesodermale gemengde tumor van de baarmoeder-afdeling gynaecologie-Obstetrie en Gynaecologie-Healthfrom.co A malignant mixed Müllerian tumor, also known as malignant mixed mesodermal tumor (MMMT) is a cancer found in the uterus, the ovaries, the fallopian tubes and other parts of the body that contains both carcinomatous (epithelial tissue) and sarcomatous (connective tissue) components EEN kwaadaardige gemengde Müller-tumor, ook gekend als kwaadaardige gemengde mesodermale tumor (MMMT) is een kanker gevonden in de baarmoeder, de eierstokken, de eileiders en andere delen van het lichaam die beide bevatten kankerverwekkend (epitheel weefsel) en sarcomateus (bindweefsel) componenten.Het is verdeeld in twee soorten, homoloog (waarbij de sarcomateuze component is gemaakt van. mixed mes·o·der·mal tu·mor a sarcoma of the body of the uterus arising in older women, composed of more than one mesenchymal tissue, especially including striated muscle cells. Synonym (s): malignant mixed müllerian tumor Farlex Partner Medical Dictionary © Farlex 201

De tumor-merkstof CA 125 was voor de operatie sterk verhoogd en daalde na de behandeling tot normale waarde. In de tumor werd adenocarcinoom, sarcoom en chondrosarcoom gevonden. Er zijn ongeveer 84 maligne mesodermale menggezwellen beschreven. De meest waarschijnlijke oorsprong van deze tumoren is de multi-potente cel van het coeloomepitheel Malignant Mixed Mesodermal Tumor (MMMT) - Early Stage With Postoperative XRT/Chemotherapy The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details The occurrence of sarcoma in a benign cystic teratoma is very rare. We report the first poorly differentiated, malignant mixed mesodermal tumor with a component of rhabdomyosarcoma to arise in a benign cystic teratoma of the ovary. The tumor was staged as FIGO IC due to capsule invasion

Mesenchyme-derived tumors tend to be characterized by simple fusion genes. Ectoderm and endoderm-derived tumors tend to be genetically unstable and cannot be characterized by a single genetic abnormality. Primitive blastomas share similar markers regardless of the organ of origin Looking for mesodermal tumor? Find out information about mesodermal tumor. A tumor composed of cells normally derived from the mesoderm. McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The... Explanation of mesodermal tumor malignant mesothelioma. malignant microcalcifications. malignant midline reticulosis. malignant mimic. malignant mixed ganglioneuronal tumor. malignant mixed mesodermal tumor. malignant mixed Müllerian tumour. malignant mole. malignant mole syndrome

IXED MESODERMAL TUMOR Of the ovary is a rare tumor which shows a characteristic histologic ap- pearance composed of carcinomatous and sarcomatous elements.' In the female genital tract, mixed mesodermal tumors are reported to occur in the uterine corpus,* uter- ine ~ervix,~ fallopian tube4 and Mixed meso tumor, while carcinosarcoma and mixed mesodermal tumor represent malignant forms. In addition to these, there is a biphasic ovarian neoplasm that has been described only in an abstract as a low grade mixed meso- dermal tumor. In this neoplasm, the stroma is hypercellular and the cells more atypica

Ovarian malignant mixed mesodermal tumor with

mesodermal tumors contained neoplastic heterologous elements (bone, cartilage, and striated muscle) in addition to carcinosarcomatous foci. The major dif- ference between the 2 groups was in survival. The median survival for patients with mixed mesodermal tumors was 6 months, whereas it was 12 months in women with carcinosarcoma mesodermal tumor (MMMT), is a rare variant of ovarian cancer, accounting for <1% of all ovarian tumors.1 MMMTs of the ovary are included in the endometrioid category because they resemble the tumors with those designations that are encountered most commonly in the endometrium.2,3 Although this tumor contains epithelia Mixed mesodermal sarcoma of the ovary is a rare clinical entity. To review the epidemiology, prognostic factors, and treatment results related to primary ovarian sarcoma at our center, a retrospective chart review of all patients referred for ovarian cancer was carried out from 1974 to 1994

MESODERMAL MIXED TUMOR OF THE UTERUS A Cytologic, Histologic, and Electyon Min-oscopic Corn-elation LAWRENCE H. BORAM, MD, ROBERT A. ERLANDSON, PHD, AND STEVEN I. HAJDU, MD A mesodermal mixed tumor of the uterus was studied by both light and elec- tron microscopy A uterine malignant mixed Müllerian tumor can be either homologous or heterologous. Similar to malignant mixed Müllerian tumors in general, they are composed or both carcinomatous (epithelial) and sarcomatous (mesodermal) components. Usually, the epithelial component dominates 2. Prevalent subtypes for the epithelioid component include

Mixed Mesodermal Tumour of the Corpus Uter

  1. A group of tumors affecting the female reproductive system, characterized by the presence of epithelial and stromal elements. It includes the following clinicopathological entities: adenofibroma, adenomyoma, Mullerian adenosarcoma, and malignant mixed mesodermal (Mullerian) tumor. [from NCI
  2. mixed mesodermal tumor, sarcoma botryoides, and carcinosarcoma. From the literature on uterine and vaginal neoplasms, McFarland collected 119 different terms, many of which have been applied to what is probably a single clinicopathological entity. Since January 1, 1946, we have studied twenty-one such tumors
  3. Mesodermal Tumors. Authors; Authors and affiliations; K. J. Zülch; Chapter. 4 Citations; 23 Downloads; Abstract. The meningiomas are in all probability the brain tumors that have been known longest. Because of the occasional production of grotesque cranial deformities,.
  4. Malignant mixed mesodermal tumor of the ovary Elbers, J.R.J.; Wagenaar, S.S. (1980) European Journal of Obstetrics & Gynecology and Reproductive Biology, volume 10, issue 1, pp. 47 - 5
  5. Fibrosarcoma is characterized as an invasive nodular tumor of mesodermal origin, with elongated central normochromatic nuclei and basophilic nucleoli. Diagnosis and Management of Neck Tumor in a Dog Third possibility suggested in literature is that of heteroplasia, which is displacement of mesodermal cells during embryonic life already destined to differentiate into cartilage.
  6. de Müller-mixed tumor geeft kwaadaardige mesodermale gemengde tumoren aan die zich in het gebied van de eierstokken of in het gebied van de eierstokken bevinden. De term Müller gemengde tumor is verouderd. Tegenwoordig worden deze tumoren genoemd carcinosarcoma of gewoon als gemengde tumor genoemd. De naam carcinosarcoom komt van het feit dat.

MESODERMAL MIXED TUMORS OF THE UTERUS EDWARD C. H. 8CHMIDT, PaM., M.1)., AND RICHARD 11. SCUUTZ, KANSAS CITY, MO. (Fronü Departments of Pathology, and Obstetrics and Gynecology, St. Duke's aospital) TUMORS composed of a variety of tissues are not uncommon iii many locations in the uch as mixed tumors of the salivary glands and embryonal sarcomas of the urinary tract Een kwaadaardige gemengde Müllerian tumor in de baarmoeder kan zowel homoloog als heteroloog zijn. Zoals kwaadaardige gemengde Müllerian tumoren in het algemeen, zijn ze samengesteld uit zowel carcinomateuze (epitheliale) als sarcomateuze (mesodermale) componenten. Meestal overheerst de epitheliale component 2

[Mixed mesodermal tumor of the ovary]

Malignant mixed mesodermal tumor of ovary

  1. These tumor samples were divided into three groups, including the ectoderm, mesoderm, and endoderm. Children cases less than 9 years old accounted for a larger proportion for the cases in the ectoderm and mesoderm groups; whereas the middle-aged and elderly individuals (from 50 to 89 years old) were more susceptible to tumors of endoderm
  2. Mesenchymous or mixed mesodermal tumor (mixed connective tissue types) Myeloma. Myeloma is cancer that originates in the plasma cells of bone marrow. The plasma cells produce some of the proteins found in blood. Leukemia. Leukemias (liquid cancers or blood cancers) are cancers of the bone marrow (the site of blood cell production)
  3. Malignant mixed Müllerian tumor, malignant mesodermal mixed tumor, metaplastic carcinoma ICD coding. ICD-O: 8980/3 - Carcinosarcoma, NOS Epidemiology. Rare ( 5% of gynecological carcinomas) Almost always in postmenopausal women (mean age: 65 years) Higher incidence in black wome
  4. N2 - We report on the pathologic findings in primary tumors and metastases in 203 cases of stage I and II endometrial carcinosarcoma (malignant mixed mesodermal tumor) subjected to hysterectomy and staging laparotomy. Metastases were studied in 40 of these cases, including 34 with positive findings in the pelvic and/or para-aortic lymph nodes
  5. Also called malignant mixed mesodermal tumor or carcinosarcoma (if homologous) Rare, < 100 reported cases, less common than leiomyosarcoma. Most tumors of cervix are extensions from endometrium; may be secondary to radiation therapy for cervical squamous cell carcinoma. Mean age 50 to 65 years, range 12 to 93 years
  6. Mixed müllerian mesodermal tumors are rare tumors of uncertain origin. Although these tumors account for 2-5% of all uterine malignancies, extragenital mixed müllerian mesodermal tumors have been reported in various locations ranging from pelvic peritoneum to diaphragm peritoneum
  7. Eleven examples of a rare group of neoplasms composed of both epithelial and mesenchymal components are reported. Ten arose from the ovary and one arose separately in the para‐ovarian region. The neoplasms are distinctive in that the stroma is more cellular than that of adenofibromas, but the epithelial component is not malignant, as in carcinosarcoma and mixed mesodermal tumors, and the.

Mixed mesodermal tumors of the uterus

A malignant mixed Müllerian tumor, also known as malignant mixed mesodermal tumor (MMMT) is a cancer found in the uterus, the ovaries, the fallopian tubes and other parts of the body that contains both carcinomatous (epithelial tissue) and sarcomatous (connective tissue) components.It is divided into two types, homologous (in which the sarcomatous component is made of tissues found in the. Mixed mesodermal tumors are highly malignant. It is be-lieved that the tumors with the prevalence of epithelial ele-ments in their structure metastasize by the lymphatic ducts, while the tumors with the prevalence of mesodermic tissues disseminate by the blood vessels (2, 6). The treatment of choice, in mixed mesodermal tumors, is surgery. A rare case of radiation-induced malignant mixed mesodermal tumor of the bladder is reported. A 78-year-old woman complained of hematuria, which originated from a polypoid tumor in the bladder 15 years after radiotherapy for squamous cell carcinoma of the uterine

MMMT - Malignant Mixed Mesodermal Tumor. Looking for abbreviations of MMMT? It is Malignant Mixed Mesodermal Tumor. Malignant Mixed Mesodermal Tumor listed as MMMT. Malignant Mixed Mesodermal Tumor - How is Malignant Mixed Mesodermal Tumor abbreviated Masterson JG, Kremper J: Mixed mesodermal tumors. Am J Obstet Gynecol 104: 693, 1969 : 79. Schaepmen-Van Geuns EJ: Mixed tumors and carcinosarcomas of the uterus evaluated five years after treatment. Cancer 25: 72, 1970 : 80. Mortel R, Koss LG, Lewis JL et al: Mesodermal mixed tumors of the uterine corpus. Obstet Gynecol 43: 248, 1974 : 8 These tumors usually develop in tissues of the female genital tract and are associated with a poor outcome. The majority of these tumors arise in the uterus, though they can also occur in the ovaries, fallopian tubes, and cervix. Very rarely, MMMTs can develop in the female peritoneum (lining of the abdominal wall)

Ten cases of extrauterine malignant mixed mesodermal tumors (MMMTs), nine ovarian, and one pelvic, are presented. One patient had a purely epithelial primary ovarian tumor and MMMT in her recurrent tumors. All the other patients had MMMT in their primary and recurrent tumors Malignant retroperitoneal tumors account for approximately 0.1 % of all malignancies and are more common than benign tumors in the retroperitoneal space [6, 7].Retroperitoneal sarcomas account for 90 % of mesodermal primary retroperitoneal malignancies, with liposarcoma, leiomyosarcoma, and malignant fibrous histiocytoma making up more than 80 % of these tumors [1, 8] MMMT - Mixed Malignant Mesodermal Tumor. Looking for abbreviations of MMMT? It is Mixed Malignant Mesodermal Tumor. Mixed Malignant Mesodermal Tumor listed as MMMT. Mixed Malignant Mesodermal Tumor - How is Mixed Malignant Mesodermal Tumor abbreviated View This Abstract Online; Carcinoma (malignant mixed müllerian [mesodermal] tumor) of the uterus and ovary. Correlation of clinical, pathologic, and immunohistochemical features in 29 cases Definition. Carcinosarcoma of the corpus uteri is a rare, malignant, mixed epithelial and mesenchymal tumor of the uterine body composed of high-grade carcinomatous and sarcomatous elements. It may present with vaginal bleeding, abnormal vaginal discharge, abdominal pain and/or pelvic mass, with a polypoid tumor sometimes protruding through the.

Two patients with highly malignant mixed mesodermal (müllerian) tumor of the ovary are presented. The tumor has the same histologic characteristics in the ovary as in its more common endometrial location, featuring a narrow range of epithelial derivatives and a variety of heterologous mesenchymal elements. The possible origin of these tumors from ovarian endometriosis is supported by the. Although simultaneous endometrial and ovarian tumors are observed occasionally, rarely are the two neoplasms histologically disparate. We report a case of simultaneous endometrial malignant mixed mesodermal tumor and ovarian serous adenocarcinoma with a single right external iliac lymph node metastasis What is GYN Carcinosarcoma (GCS) or MMMT? Another Term for GYN Carcinosarcoma is malignant mixed Müllerian tumor or MMMT. GYN carcinosarcoma is a malignant neoplasm found in the uterus, the ovaries, the fallopian tubes and other parts of the body that contains both carcinomatous (epithelial tissue) and sarcomatous (connective tissue) components. It is divided into Continue reading.

Maligne mesodermale gemengde tumor van de baarmoeder

Neonatal tumors encompass a group of heterogeneous neoplasms that demonstrate anatomic locations, behavior patterns, histologic features, and treatment responses that are distinct from neoplasms found in older children. The majority of neonatal tumors are benign, with malignant lesions accounting for only 2% of childhood cancers Three cases of mixed mesodermal tumors of the urinary bladder characterized by the simultaneous occurrence of malignant epithelial and mesenchymal elements in the same tumor are reported. Integrated therapy consisting of preoperative radiotherapy followed by radical cystectomy is recommended

Goedaar dige tumor en kun nen d odelijk zijn. 43. T er atome n zijn kiemceltumoren met ecto-, ent o- en mesodermale diff erentiaties. 44. RIP in glandula par otis r echts k an mondhoek niet openen → a denoom van de gla ndula parotis en tumor van d e . nervus facialis. 45 Mesodermal tumors! Odontogenic myxoma, Benign cementoblastoma! Central odontogenic fibroma AOT! Adenomatoid Odontogenic Tumor! Most common location : maxillary canine and premolar region. 2:1 female to male ratio. Average age = ~16 yrs! Tumors contain specks of calcified material! Low recurrence rat Moreover, the occurrence of an 10. extragenital malignant mixed mesodermal tumor arising in association with a primary serous papillary carcinoma of the ovary or peritoneum further supports this hypothesis of a common mullerian epithelial stem-cell origin for ll. both genital and extragenital mullerian-type neoplasms.1. 2.3. 4.5. 6.7.FIG.

Aspirate from a metastatic tumor of a mixed mesodermal tumor arising from the omentum showed similar malignant endometrial stroma cells, irregular tight clusters of malignant glandular cells having scanty but well‐defined cytoplasm and vesicular nuclei with conspicuous nucleoli, and fragments of atypical smooth muscle tissue Clinicopathologic data are presented for 22 cases of malignant mixed mesodermal tumors of the ovary of both homologous and heterologous types. The results substantiate previous reports of low parity in the almost exclusively postmenopausal women with this tumor. Symptoms were the same as for ovarian malignancy in general. More than half the patients presented with stage III or IV disease. De tumor gaat delen op de plek en de cellen verliezen hun affiniteit. De celadhesie moet verminderd worden. Direct na de vorming van deze somieten worden de somieten onderverdeeld in delen welke specifieke mesodermale componenten vormen. De eerste subdivisie die ontstaan zijn de sclerotomen. Deze zullen de wervels vormen Uterine sarcomas comprise less than 1% of gynecologic malignancies and 2% to 5% of all uterine malignancies. [ 1] The following tumors arise primarily from three distinct tissues: Carcinosarcomas arising in the endometrium, in other organs of mullerian origin, and accounting for 40% to 50% of all uterine sarcomas The occurrence of sarcoma in a benign cystic teratoma is very rare. We report the first poorly differentiated, malignant mixed mesodermal tumor with a component of rhabdomyosarcoma to arise in a benign cystic teratoma of the ovary. The tumor was staged as FIGO IC due to capsule invasion. Although combination chemotherapy of cisplatin, ifosfamide and mesna, was instituted, the disease took a.

Uterine smooth muscle tumors that show some worrisome histologic features (i.e. necrosis, nuclear atypia, or mitoses), but do not meet all diagnostic criteria for leiomyosarcoma, fall into the category of atypical smooth muscle tumors (STUMP) (Box 2). 3 This diagnosis, however, should be used sparingly and every effort should be made to classify a smooth muscle tumor into a specific category. Carcinosarcoma of Uterus, Malignant Mixed Mesodermal Tumor of the Uterus, Corpus Uteri Malignant Mixed Mesodermal Tumor, Uterine Corpus Malignant Mixed Müllerian Tumor, Mixed Mullerian Sarcoma of the Uterus, Mixed Mullerian Sarcoma of Uterus, Uterine Mixed Müllerian Sarcoma, Carcinosarcoma of Uterine Body, Uterine Corpus Malignant Mixed Mesodermal Neoplasm, Mixed Müllerian Sarcoma of the.

Mixed Müllerian tumor - Wikipedi

Effect of irradiation on mixed mesodermal tumors of the uterus. Download. The material is further evaluated for the effect of grade within stage for all stages. For example, Stage III Grade 1 lesion's five year survival IV showed five is 73%, Grade 2 70%, and Grade 3 and 4 combined 23%. Stage zyxwvutsrqponmlkjihgfedcbaZYXW year survival of 20%. While ETV6- NTRK3 fusion is common in infantile fibrosarcoma, NTRK1/3 fusion in pediatric tumors is scarce and, consequently, not well known. Herein, we evaluated for the presence of NTRK1/3 fusion in pediatric mesenchymal tumors, clinicopathologically and immunophenotypically. We reviewed nine NTRK fusion-positive pediatric sarcomas confirmed by fluorescence in situ hybridization and/or next.

Gemengde Müller-tumor - Mixed Müllerian tumo

Mixed mesodermal tumors and carcinosarcomas of the ovary are unusual tumors, with less than 300 cases reported in the literature [2,6]. This study confirms previous reports that these malignancies are rapidly progressive and almost uniformly fatal [7-10]. Clinically, presenting. mes·o·derm. (mĕz′ə-dûrm′, mĕs′-) n. The middle embryonic germ layer, lying between the ectoderm and the endoderm, from which connective tissue, muscle, bone, and the urogenital and circulatory systems develop. mes′o·der′mal, mes′o·der′mic adj. American Heritage® Dictionary of the English Language, Fifth Edition Epithelial-mesenchymal transition (EMT) is a process in which epithelial cells acquire mesenchymal features. In cancer, EMT is associated with tumor initiation, invasion, metastasis, and resistance to therapy. Recently, it has been demonstrated that EMT is not a binary process, but occurs through distinct cellular states. Here, we review the recent studies that demonstrate the existence of. Abstract. A rare case of radiation-induced malignant mixed mesodermal tumor of the bladder is reported. A 78-year-old woman complained of hematuria, which originated from a polypoid tumor in the bladder 15 years after radiotherapy for squamous cell carcinoma of the uterine cervix

Uterine Cancers Resources. Foundation for Women's Cancer 1-312-578-1439. American Cancer Society 1-800-227-2345. Cancer.net 1-888-651-3038. National Cancer Institute 1-800-422-6237. The American College of Obstetricians and Gynecologists. Medication & Financial Assistance Resources Interactief college 4 ic3: embryologie de embryologiekennislijn heeft als doel de vroege embryonale ontwikkeling en de beginselen van de morfogenese bij t Coexistent choriocarcinoma and malignant mixed mesodermal tumor of the uterus. Gynecol Oncol. 2000; 79(3) RESULTS: The patient's uterine tumor contained syncytiotrophoblastic and cytotrophoblastic cells that stained positively for the beta subunit of human chorionic gonadotrophin consistent with uterine choriocarcinoma An unusual tumor of the ureter in an elderly man is reported. The tumor showed evidence of epithelial and mesenchymal differentiation based on histological and immunocytochemical criteria, and it behaved aggressively, comparable to that seen in other mixed tumors of this type arising from elsewhere within the genitourinary tract Clinical Trials on Mixed Tumor, Mesodermal . Total 11 results. NCT00231842. Completed. Adjuvant Radiation Therapy With Ifosfamide in Patients With Mixed Mesodermal Tumors of the Uterus. Conditions: Uterine Cancer . NCT00505492. Terminated. Malignant Mixed Mesodermal Tumor (MMMT) - Early Stage With Postoperative XRT/Chemotherapy

Learn in-depth information on Malignant Mesodermal Mixed Tumor of Cervix, its causes, symptoms, diagnosis, complications, treatment, prevention, and prognosis Two women (0.15%) were found to have endometrial stromal sarcoma and none was found to have a mixed mesodermal tumor. During the same interval, nine additional patients were found to have uterine sarcomas, and for these the preoperative diagnosis was sarcoma in four, endometrial cancer in three, ovarian cancer in one, and prolapsed uterus in one These tumors can grow and spread quickly. Endometrial stromal sarcoma (ESS) ESS tumors start in the supporting connective tissue (stroma) of the lining of the uterus (the endometrium). These cancers are rare. If the tumor is low grade, the cancer cells do not look very different from normal cells and the tumor tends to grow slowly

Mixed mesodermal tumor definition of mixed mesodermal

Some of the examples include mixed mesodermal tumor, carcinosarcoma, adenosquamous carcinoma and teratocarcinoma. Blastomas are another type that involves embryonic tissues. Classification by grad Case Selection and Mutational Analysis. A total of 57 cases of ovarian carcinoma, which included 43 high-grade serous ovarian/peritoneal carcinomas, 2 malignant mesodermal mixed tumors (MMMTs), 2. The most common type of testis cancer is a germ cell tumor. There are two main types of GCT: seminoma and nonseminomatous germ cell tumors (NSGCT). There are several differences between seminomas and NSGCT, but the initial distinction is based on how the tumor looks under the microscope Brachyury (from Greek βραχύς, short and ουρά, tail) is a protein that, in humans, is encoded by the TBXT (T-box transcription factor T) gene. Brachyury functions as a transcription factor within the T-box family of genes. Brachyury homologs have been found in all bilaterian animals that have been screened, as well as the freshwater cnidarian Hydra

(Mixed malignant mesodermal tumor) Alenka Repše Fokter University Clinical Centre Maribor, Slovenia. Clinical presentationClinical presentation • 70-years old patient • Preventive cervical smear (conventional)Preventive cervical smear (conventional) • No clinical symptoms/sign Download PDF: Sorry, we are unable to provide the full text but you may find it at the following location(s): https://dspace.library.uu.nl/b... (external link Malignant mixed mesodermal tumors rarely occur in extragenital sites. An 80-year-old patient presented with a malignant mixed mesodermal tumor, consisting of papillary serous adenocarcinoma and chondrosarcomatous components. The patient refused further treatment following surgery and died of disease 2.5 months later. Based on the present case and a review of the literature, primary.